A well-known metaphor: a house is not a mere collection of bricks. It is, rather, a collection of bricks that has been organized in a certain structure. Organizing information into structure seems to be something our brains are good at. What if this organization is the means by which our brain comprehends, stores, and transmits information? In other words, the structure of information is all there is. "Meaning" may simply be certain types of structure of information that our brain distinguishes from others. When this distinction occurs, the brain provides us with emotional impulses, which creates this sensation of "aha, that is quite deep". If something like this is true, then the brain ought to be programmed to recognize structure in a way that is synchronized with the structure of the universe surrounding us, since those "aha" moments led us to a point where we can make predictions about nature, communicate over a large distance, etc.
It is difficult to test out such a theory since perceived information is usually matched with existing knowledge in our subconscious... so it is difficult to isolate a describable portion of self-contained information, which would be necessary for a rigorous study of how the structure of information determines the meaning. Except perhaps in an art form, where the "meaning" is least dependent on existing knowledge, such as music.
Here is my (almost) first attempt at the study of how a meaning of a musical piece could be interpreted via the structure of the organization of its sounds. I improvised this short piece:
And then isolated various layers of its musical structure: